This page was produced as an assignment for Genetics 564, an undergraduate capstone course at The University of Wisconsin - Madison.
What is a model organism?
Model organisms are non human species that are used for scientific research to understand biological processes and disease in humans. The 6 of the most commonly used model organisms are monkeys, mice, zebrafish, drosophila, C. elegans, and E. coli. The characteristics of different organisms make them better suited for experiments depending on what biological process you're trying to study.
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Model Organism Databases for Amyloid Precursor Protein (APP)
Discussion
To characterize the upstream promoter region, a mouse would be the ideal model organism because they exhibit a strong homogeny with their human counter part and can be used to easily quantify the disease phenotype of Alzheimer's diseases behavior.
References
[1] Mouse Genome Database. 2017. About MGI. [Web]. http://www.informatics.jax.org/mgihome/projects/aboutmgi.shtml
Images:
http://www.yourgenome.org/facts/what-are-model-organisms
Images:
http://www.yourgenome.org/facts/what-are-model-organisms